Acute phase reactants (APR) are inflammation markers that exhibit significant changes in serum concentration during inflammation. These are also important mediators produced in the liver during acute and chronic inflammatory states.
Which are acute phase reactant proteins?
Acute-phase proteins (APPs) are a class of proteins whose plasma concentrations increase (positive acute-phase proteins) or decrease (negative acute-phase proteins) in response to inflammation. This response is called the acute-phase reaction (also called acute-phase response).
Is MBL an acute-phase protein?
It has been suggested that MBL acts as an acute-phase protein responding to inflammation, consistent with its role in early infection .